Psychological impact of recall on women with BRCA mutations undergoing MRI surveillance. The Breast, Oct 2011, Vol. 20(5), p.424-430
Spiegel, TN, et al.
http://www.thebreastonline.com/article/PIIS0960977611000944/abstract?rss=yes
The addition of magnetic resonance imaging (MRI) to mammography for surveillance of women with BRCA mutations significantly increases sensitivity but lowers specificity. This study aimed to examine whether MRI surveillance, and particularly recall, is associated with increased anxiety, depression, or breast cancer worry/distress. While breast MRI surveillance did not have a detrimental psychological impact on women with a BRCA1 or BRCA2 mutation, recalling these very high-risk women for further imaging after a false positive MRI scan temporarily increased their global anxiety.
