Tuesday, 8 November 2011

Breast cancer after hormone replacement therapy

Breast cancer after hormone replacement therapy: does prognosis differ in preimenopausal and postmenopausal women? The Breast, Oct 2011, Vol. 20(5), p.448-454

A.K. Baumgärtner, AK, et al.

Hormone replacement therapy (HRT) has been associated with higher incidence of breast cancer in postmenopausal women, but it is unclear if breast cancers developing after HRT use have different prognosis. 1053 women with hormone receptor positive non-metastasized breast cancer were analyzed in a retrospective trial, stratifying by HRT use before diagnosis. In this retrospective analysis postmenopausal HRT users seemed to have a better breast cancer prognosis. For perimenopausal HRT users however, a trend towards worse prognosis was found.