Monday, 22 October 2012

The impact of mammographic screening on breast cancer mortality in Europe

The impact of mammographic screening on breast cancer mortality in Europe: a review of observational studies. Journal of medical screening, Sept. 2012, Vol. 19 Supp.1, p.14-25.

Broeders, M., et al.

http://jms.rsmjournals.com/content/19/suppl_1/14.full.pdf+html


Valid observational designs are those where sufficient longitudinal individual data are
available, directly linking a woman’s screening history to her cause of death. From such studies, the
best ‘European’ estimate of breast cancer mortality reduction is 25–31% for women invited for
screening, and 38–48% for women actually screened. Much of the current controversy on breast
cancer screening is due to the use of inappropriate methodological approaches that are unable to capture the true effect of mammographic screening.