Infiltration of epinephrine in reduction mammoplasty: a systematic review of the literature. Plastic & reconstructive surgery, October 2012, Vol. 130(4), p.773-778.
Hardwicke, J.T., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/10000/Infiltration_of_Epinephrine_in_Reduction.7.aspx
Evidence of the benefit of dilute epinephrine infiltration before reduction mammaplasty is provided by several controlled trials. Despite variation in operative technique and data collection, a reduction in intraoperative blood loss has been shown. The aim of this review of the literature is to weigh the available evidence with respect to reducing blood loss during surgery and other outcome measures such as postoperative drainage.