Optimal adjuvant therapy for very young brest cancer patients. The Breast, Aug 2011, vol. 20(4), p.297-302.
Francis, PA.
http://www.thebreastonline.com/article/PIIS0960977611001032/abstract?rss=yes
Approximately one in forty women diagnosed with early breast cancer is very young (<35 years) and this age group has a worse prognosis. The inferior prognosis in very young women appears to have two aspects. Very young women present more frequently with tumors with adverse histo-pathologic features. However, even when the histo-pathologic features appear favorable (ie. endocrine responsive tumors), analyses suggest that very young women with hormone receptor positive tumors are a sub-group at particular risk for adverse outcomes, compared to older premenopausal women with similar tumors
