Wednesday 3 August 2011

High-dose chemotherapy with stem-cell support gives no apparent survival benefit in breast cancer

High-dose chemotherapy with stem-cell support gives no apparent survival benefit in breast cancer. J Clin Oncol, published early online 18 July 2011

Glare, J. (summary)

http://www.nelm.nhs.uk/en/NeLM-Area/News/2011---July/20/High-dose-chemotherapy-with-stem-cell-support-gives-no-apparent-survival-benefit-in-breast-cancer/

Two meta-analyses published early online by the Journal of Clinical Oncology examine the evidence on high-dose chemotherapy with stem-cell support in high-risk primary and in metastatic breast cancer: both found that while the technique produced small increases in relapse-free survival, it did not significantly prolong overall survival.