Association between treatment with brachytherapy vs whole breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancer. JAMA, 2012, Vol. 307(17), p.1827-1837.
Smith, G.L., et al.
http://jama.ama-assn.org/content/307/17/1827.short?rss=1
Brachytherapy is a radiation treatment that uses an implanted radioactive source. In recent years, use of breast brachytherapy after lumpectomy for early breast cancer has increased substantially despite a lack of randomized trial data comparing its effectiveness with standard whole-breast irradiation (WBI).
Thursday, 3 May 2012
Are pfanennsteil scars a boon or a curse for DIEP flap breast reconstructions?
Are pfanennsteil scars a boon or a curse for DIEP flap breast reconstructions? Plastic and reconstructive surgery, April 2012, Vol. 129(4), p.797-805.
Mahajan, A.L., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/04000/Are_Pfannenstiel_Scars_a_Boon_or_a_Curse_for_DIEP.1.aspx
Abdominal incisions and their subsequent scarring alter the vascular architecture of the abdominal pannus. This is of significance when reconstructing the breast with the deep inferior epigastric perforator (DIEP) flap. This study aimed to objectively investigate the impact of the lower abdominal Pfannenstiel scar in utilizing the DIEP flap.
Mahajan, A.L., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/04000/Are_Pfannenstiel_Scars_a_Boon_or_a_Curse_for_DIEP.1.aspx
Abdominal incisions and their subsequent scarring alter the vascular architecture of the abdominal pannus. This is of significance when reconstructing the breast with the deep inferior epigastric perforator (DIEP) flap. This study aimed to objectively investigate the impact of the lower abdominal Pfannenstiel scar in utilizing the DIEP flap.
Neglecting to screen women between the ages of 40-49 years with mammography
Neglecting to screen women between the ages of 40-49 years with mammography: What is the impact on breast cancer diagnosis? AJR, May 2012, Vol. 198(5), p.1218-1222.
Kremer, M.E., et al.
http://www.ajronline.org/content/198/5/1218.abstract?rss=1
The purpose of this study was to compare breast cancer stage at diagnosis in two groups of women between 40 and 49 years old: women undergoing screening mammography and women with a symptom needing diagnostic workup.
Kremer, M.E., et al.
http://www.ajronline.org/content/198/5/1218.abstract?rss=1
The purpose of this study was to compare breast cancer stage at diagnosis in two groups of women between 40 and 49 years old: women undergoing screening mammography and women with a symptom needing diagnostic workup.
The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction
The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction. Plastic & reconstructive surgery, May 2012, Vol. 129(5), p.1049-1058.
Weichman, K.E., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2012/05000/The_Use_of_Acellular_Dermal_Matrix_in_Immediate.5.aspx
Acellular dermal matrix is commonly used in implant-based breast reconstruction to allow for quicker tissue expansion with better coverage and definition of the lower pole of the breast. This study was performed to analyze complications associated with its use in immediate two-stage, implant-based breast reconstruction and to subsequently develop guidelines for its use.
Weichman, K.E., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2012/05000/The_Use_of_Acellular_Dermal_Matrix_in_Immediate.5.aspx
Acellular dermal matrix is commonly used in implant-based breast reconstruction to allow for quicker tissue expansion with better coverage and definition of the lower pole of the breast. This study was performed to analyze complications associated with its use in immediate two-stage, implant-based breast reconstruction and to subsequently develop guidelines for its use.
Assessment of zonal perfusion using intraoperative angiography during abdominal flap breast reconstruction
Assessment of zonal perfusion using intraoperative angiography during abdominal flap breast reconstruction. Plastic & reconstructive surgery, April 2012, Vol. 129(4), p.618e-624.
Losken, A., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/04000/Assessment_of_Zonal_Perfusion_Using_Intraoperative.5.aspx
There is an ongoing debate about the reliability of various lower abdominal flaps for breast reconstruction. The authors evaluate in vivo perfusion of these flaps to objectively determine which techniques and which skin island zones had better perfusion.
Losken, A., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/04000/Assessment_of_Zonal_Perfusion_Using_Intraoperative.5.aspx
There is an ongoing debate about the reliability of various lower abdominal flaps for breast reconstruction. The authors evaluate in vivo perfusion of these flaps to objectively determine which techniques and which skin island zones had better perfusion.
Implant-based two-stage breast reconstruction in the setting of radiation injury
Implant-based two-stage breast reconstruction in the setting of radiation injury: An outcome study. Plastic & reconstructive surgery, April 2012, Vol. 129(4), p.817-823.
Lin, K.Y., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2012/04000/Implant_Based,_Two_Stage_Breast_Reconstruction_in.6.aspx
More women with breast cancer who either have already had radiation therapy or will be getting radiation therapy as part of their treatment protocol are now seeking implant-based breast reconstruction. The literature on the success of this type of reconstruction in the setting of radiation injury is mixed.
Lin, K.Y., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2012/04000/Implant_Based,_Two_Stage_Breast_Reconstruction_in.6.aspx
More women with breast cancer who either have already had radiation therapy or will be getting radiation therapy as part of their treatment protocol are now seeking implant-based breast reconstruction. The literature on the success of this type of reconstruction in the setting of radiation injury is mixed.
Medullary carcinoma of the breast: MRI findings
Medullary carcinoma of the breast: MRI findings. AJR, May 2012, Vol. 198(5), W482-487.
Jeong, S.J., et al.
http://www.ajronline.org/content/198/5/W482.abstract?rss=1
The objective of our study was to describe the MRI findings of medullary carcinoma of the breast and to correlate those findings with the histopathologic findings.
Jeong, S.J., et al.
http://www.ajronline.org/content/198/5/W482.abstract?rss=1
The objective of our study was to describe the MRI findings of medullary carcinoma of the breast and to correlate those findings with the histopathologic findings.
Thursday, 19 April 2012
Accuracy of magnetic resonance in suspicious breast lesions
Accuracy of magnetic resonance in suspicious breast lesions: a systematic quantitative review and meta-analysis. Breast Cancer Research and Treatment 2011; Vol. 126(2), p. 273-285.
Medeiros L.R., et al.
http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?ID=12011004113
This review concluded that breast magnetic resonance imaging (MRI) was a useful preoperative test for differentiating between breast cancer/high-risk lesions and benign lesions.
Medeiros L.R., et al.
http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?ID=12011004113
This review concluded that breast magnetic resonance imaging (MRI) was a useful preoperative test for differentiating between breast cancer/high-risk lesions and benign lesions.
Cost-effectiveness of contralateral prophylactic mastectomy
Cost-effectiveness of contralateral prophylactic mastectomy versus routine surveillance in patients with unilateral breast cancer. Journal of Clinical Oncology 2011; Vol. 29(22), p. 2993-3000.
Zendejas, B., et al.
http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?ID=22011001483
Zendejas, B., et al.
http://www.crd.york.ac.uk/crdweb/ShowRecord.asp?ID=22011001483
The objective was to evaluate the cost-effectiveness of contralateral prophylactic mastectomy versus routine surveillance in patients with unilateral breast cancer. The authors concluded that contralateral mastectomy was cost-effective, compared with surveillance, for patients younger than 70 years.
Tuesday, 10 April 2012
Breast clinic triage tool
Breast clinic triage tool: Telephone assessment of new referrals. The breast, April, 2012, Vol. 21(2), p.215-217.
Cusack, L., et al.
Efficient systems to triage increasing numbers of new referrals to breast clinics are needed, to optimise the management of patients with cancer and benign disease.
Combination of two local flaps for large defects after breast conserving surgery
Combination of two local flaps for large defects after breast conserving surgery. The breast, April 2012, Vol. 21(2), p.194-198.
Lee, J., et al.
Oncoplastic surgery is a technique for wide excision of breast cancer without compromising the natural shape of the breast. We have combined two local flaps, referred to as a ‘combined local flap’, for large defects of the breast after a partial mastectomy.
Improved sub-areolar breast tissue removal in nipple-sparing mastectomy using hydrodissection
Improved sub-areolar breast tissue removal in nipple-sparing mastectomy using hydrodissection. The breast, April 2012, Vol. 21(2), p.190-193.
Folli, S., et al.
We report on a new technique of dissection of the nipple-areola-complex (NAC) in nipple-sparing mastectomy (NSM). NACs removed due to the presence of tumor cells beneath them were histologically examined for the presence of normal breast glandular tissue.
A critical review of women's sleep-wake patterns in the context of neo-/adjuvant chemotherapy
A critical review of women's sleep-wake patterns in the context of neo-/adjuvant chemotherapy for early-stage breast cancer. The breast, April 2012, Vol. 21(2), p.128-141.
Kotronoulas, G., et al.
Complaints of poor nocturnal sleep and daytime dysfunction may be frequent among women receiving chemotherapy for breast cancer. A critical review of the literature was conducted, which aimed at summarising and critically analysing findings regarding sleep in women with early-stage breast cancer across neo-/adjuvant chemotherapy treatment.
Clinical review - breast adenoid cystic carcinoma
Clinical review - breast adenoid cystic carcinoma. The breast, April 2012, Vol. 21(2), p.124-127.
Boujelbene, N. et al.
ACC of the breast has a favourable prognosis. An accurate diagnosis and appropriate treatment are therefore important.
Evaluation of the evidence on staging imaging for detection of asymptomatic distant metastases in newly diagnosed breast cancer
Evaluation of the evidence on staging imaging for detection of asymptomatic distant metastases in newly diagnosed breast cancer. The breast, April 2012, Vol. 21(2), p.112-123.
Brennan, M.E., & Houssami, N.
While guidelines recommend against routine use of staging imaging to detect asymptomatic distant metastases (DM) in newly diagnosed breast cancer (BC), modern imaging technologies may have improved detection capability and may have a role in some cases.
Anaplastic large cell lymphoma and breast implants
Anaplastic large cell lymphoma and breast implants: Five Australian cases. Plastic & reconstructive surgery, April 2012, Vol. 129(4), p.610e-617e.
Taylor, K.O., et al.
Textured surface implants only became widely used in the 1990s and therefore were not significantly represented in the large cohort studies of breast implant safety undertaken in the early 1990s. The diagnosis of anaplastic large cell lymphoma in the breast needs to be considered in patients, particularly those presenting with a periprosthetic seroma 6 months or more after breast implant insertion.
Imaging features of primary breast sarcoma
Imaging features of primary breast sarcoma. AJR, April, 2012, Vol. 198(4), p. W386-W393.
Smith, T.B., et al.
Primary breast sarcoma has imaging features that are not typically seen in infiltrating ductal carcinoma. A large oval hypervascular mass with indistinct margins should raise the suspicion for a primary breast sarcoma and prompt biopsy.
Background parenchymal enhancement on breast MRI
Background parenchymal enhancement on breast MRI: Impact on diagnostic performance. AJR, April, 2012, vol. 198(4), p. W373-W380.
DeMartini, W.B., et al.
Increased background parenchymal enhancement on breast MRI is associated with younger patient age and higher abnormal interpretation rate. However, it is not related to significant differences in positive biopsy rate, cancer yield, sensitivity, or specificity of MRI.
Breast cancer screening - time to move forward?
Breast cancer screening - time to move forward? The lancet, April 2012, Vol. 379(9823), p.1289-90.
Cuzick, J.
Peter Gøtzsche's Mammography Screening: Truth, Lies and Controversy provides more insight into the polarisation and irrationality of the debate on breast cancer screening than any useful information about the impact of screening in reducing breast cancer mortality.
Detection of breast cancer
Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk. JAMA, April 2012, Vol. 307(13), p.1394-1404.
Berg, W.A., et al.
The addition of screening ultrasound or MRI to mammography in women at increased risk of breast cancer resulted in not only a higher cancer detection yield but also an increase in false-positive findings.
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