by Xiaohan Ren, Xiaoqin Wang, Jiaru Sun, Zhaozhao Hui,
Shuangyan Lei, Caihua Wang, Mingxu Wang
The Breast: Published: March 27, 2022
Background
Cognitive impairment has a great negative impact on quality
of life for breast cancer survivors. Emerging evidence suggested that physical
exercise can improve cognitive function in order adults with Alzheimer's
disease. However, less is known about the effects of physical exercise on
cognitive function for breast cancer survivors. The purpose of this
meta-analysis was to evaluate the effect of physical exercise on cognitive
function in breast cancer survivors.
Methods
EMBASE, the Cochrane Library, Web of Science and PubMed were
searched from the establishment of the databases to June 2021. Randomized
controlled trials were included. All analysis were conducted using the Revman
5.3.
Results
12 studies (936 participants) indicated that exercise
improved self-reported cognitive function (MD 10.12, 95% CI [5.49,14.76],
p < 0.0001), cognitive fatigue (MD -5.41, 95% CI [-10.31,-0.51],
p = 0.03) and executive function (MD -13.63, 95% CI [-21.86,-5.39],
p = 0.0001).
Conclusion
Physical exercise can improve cognitive function for breast
cancer survivors, particularly in self-reported cognitive function, and
executive function. Future studies need to explore the effect of exercise on
cognitive function from the frequency and duration of exercise.
