Bertozzi, N et al
European
review for medical and pharmacological sciences; Jun 2017; vol. 21 (no. 11); p.
2572-2585
Breast
cancer is the most common female cancer in Western populations, affecting 12.5%
of women, with 1.38 million patients per year. Breast-conserving surgery
followed by postoperative radiotherapy replaced the radical and
modified-radical procedures of Halsted and Patey as the standard of care for
early-stage breast cancer once the overall and disease-free survival rates of breast-conserving
surgery were demonstrated to be equivalent to those of mastectomy. However,
excision of >20% of breast tissue, low or centrally located cancer, and
large-sized breasts with various grades of breast ptosis, result a in
unacceptable cosmetic outcomes. Oncoplastic breast surgery evolved from the
breast-conserving surgery by broadening its general indication to achieve wider
excision margins without compromising on the cosmetic outcomes....
