Monday 24 November 2014

Treatment patterns and duration in post-menopausal women with HR+/HER2

Treatment patterns and duration in post-menopausal women with HR+/HER2 - metastatic breast cancer in the US: a retrospective chart review in community oncology practices.Current Medical Research and Opinion, Nov. 2014.

Macalalad, A.R., et al.

http://informahealthcare.com/doi/abs/10.1185/03007995.2014.980885

Clinical guidelines prefer endocrine therapy (ET) as initial treatment for post-menopausal women with hormone receptor positive (HR+)/human epidermal growth factor receptor 2 negative (HER2−) metastatic breast cancer (mBC). Chemotherapy (CT) should be reserved for patients who develop symptomatic visceral disease or have no clinical benefit after three sequential ET regimens. It is unclear if real-world clinical practice reflects these guidelines.