Breast conserving surgery using the round block technique combined with partial reconstruction using the latissimus dorsi flap. The breast, Feb 2013, Vol. 22(1), p.98-99.
Zaha, H. and Onomura, M.
http://www.thebreastonline.com/article/PIIS0960977612002263/abstract?rss=yes
The round block technique (RBT) is one of the frequently used volume displacement procedures in oncoplastic breast surgery. We report a useful technique which combines RBT with immediate partial breast reconstruction using the latissimus dorsi flap (LD flap) for breast-conserving surgery (BCS).
Thursday, 31 January 2013
Pre-operative factors indicating risk of multiple operations versus a single operation in women undergoing surgery for screen detected breast cancer
Pre-operative factors indicating risk of multiple operations versus a single operation in women undergoing surgery for screen detected breast cancer. The breast, Feb. 2013, Vol. 22(1), p.78-82.
O'Flynn, E.A.M., et al.
http://www.thebreastonline.com/article/PIIS0960977612001294/abstract?rss=yes
We aim to identify preoperative factors at diagnosis which could predict whether women undergoing wide local excision (WLE) would require further operations. 1593 screen-detected invasive and non-invasive breast cancers were reviewed. Age, presence of ductal carcinoma in situ (DCIS), invasive cancer size on mammography, mammographic sign, tumour type, grade and confidence of the radiologist in malignancy were compared.
O'Flynn, E.A.M., et al.
http://www.thebreastonline.com/article/PIIS0960977612001294/abstract?rss=yes
We aim to identify preoperative factors at diagnosis which could predict whether women undergoing wide local excision (WLE) would require further operations. 1593 screen-detected invasive and non-invasive breast cancers were reviewed. Age, presence of ductal carcinoma in situ (DCIS), invasive cancer size on mammography, mammographic sign, tumour type, grade and confidence of the radiologist in malignancy were compared.
Implication of breast cancer phenotype for patients with leptomeningeal carcinomatosis
Implication of breast cancer phenotype for patients with leptomeningeal carinomatosis. The breast, Feb. 2013, Vol. 22(1), p.19-23.
Torrejon, D., et al.
http://www.thebreastonline.com/article/PIIS096097761200210X/abstract?rss=yes
We aimed to study the implications of breast cancer (BC) subtypes for the development and prognosis of leptomeningeal carcinomatosis (LC).
Torrejon, D., et al.
http://www.thebreastonline.com/article/PIIS096097761200210X/abstract?rss=yes
We aimed to study the implications of breast cancer (BC) subtypes for the development and prognosis of leptomeningeal carcinomatosis (LC).
Do primary mammary osteosarcoma and chondrosarcoma exist?
Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours. The breast, Feb. 2013, Vol. 22(1), p.13-18.
Rakha, E.A., et al.
http://www.thebreastonline.com/article/PIIS0960977612001968/abstract?rss=yes
The existing literature describing the clinicopathological features and behaviour of matrix-producing (MP) malignant breast tumours presents conflicting results. As a consequence it remains uncertain whether these tumours should be treated as sarcoma and managed by a specialist sarcoma team or treated using the same principles as conventional ductal carcinoma, a dilemma that prompted this study. Improved understanding of the clinicopathological characteristics of primary mammary MP-sarcomas, namely osteosarcoma and chondrosarcoma, is required.
Rakha, E.A., et al.
http://www.thebreastonline.com/article/PIIS0960977612001968/abstract?rss=yes
The existing literature describing the clinicopathological features and behaviour of matrix-producing (MP) malignant breast tumours presents conflicting results. As a consequence it remains uncertain whether these tumours should be treated as sarcoma and managed by a specialist sarcoma team or treated using the same principles as conventional ductal carcinoma, a dilemma that prompted this study. Improved understanding of the clinicopathological characteristics of primary mammary MP-sarcomas, namely osteosarcoma and chondrosarcoma, is required.
Efficacy of HER2-targeted therapy in metastatic breast cancer
Efficacy of HER2-targeted therapy in metastatic breast cancer. Monoclonal antibodies and tyrosine kinase inhibitors. The breast, Feb 2013, Vol. 22(1), p.1-12.
Nielsen, D.L., et al.
http://www.thebreastonline.com/article/PIIS0960977612001944/abstract?rss=yes
Nielsen, D.L., et al.
http://www.thebreastonline.com/article/PIIS0960977612001944/abstract?rss=yes
Therapies targeting the human epidermal growth factor receptor (HER) 2 are effective in metastatic breast cancer (MBC). We review the efficacy of HER2-directed therapies, focussing on monoclonal antibodies and tyrosine kinase inhibitors targeting HER2 that have been tested in phase II–III studies in MBC.
The use of dermal autograft as an adjunct to breast reconstruction with tissue expanders
The use of dermal autograft an an adjunct to breast reconstruction with tissue expanders. Plastic and reconstructive surgery, Dec. 2012, Vol. 130(6), p.1179-85.
Rinker, B.
http://journals.lww.com/plasreconsurg/Abstract/2012/12000/The_Use_of_Dermal_Autograft_as_an_Adjunct_to.2.aspx
A cellular dermal matrices are commonly used in breast reconstruction but add cost to the procedure and have been associated with complications. Dermal autograft may represent a useful alternative to matrices.
Rinker, B.
http://journals.lww.com/plasreconsurg/Abstract/2012/12000/The_Use_of_Dermal_Autograft_as_an_Adjunct_to.2.aspx
A cellular dermal matrices are commonly used in breast reconstruction but add cost to the procedure and have been associated with complications. Dermal autograft may represent a useful alternative to matrices.
A systematic review of antibiotic use and infection in breast reconstruction
A systematic review of antibiotic use and infection in breast reconstruction: What is the evidence? Plastic and reconstructive surgery, Jan 2013, Vol. 131(1), p.1-13.
Phillips, B.T., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/01000/A_Systematic_Review_of_Antibiotic_Use_and.1.aspx
The literature reports overall complication rates in breast reconstruction to be as high as 60 percent. Infection rates can exceed 20 percent, much higher than anticipated in clean elective surgery. There is no consensus among surgeons regarding the necessary duration of antibiotic prophylaxis, although the Centers for Disease Control and Prevention guidelines suggest only 24 hours. This systematic review examines antibiotic regimens and associated infection rates in breast reconstruction.
Phillips, B.T., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/01000/A_Systematic_Review_of_Antibiotic_Use_and.1.aspx
The literature reports overall complication rates in breast reconstruction to be as high as 60 percent. Infection rates can exceed 20 percent, much higher than anticipated in clean elective surgery. There is no consensus among surgeons regarding the necessary duration of antibiotic prophylaxis, although the Centers for Disease Control and Prevention guidelines suggest only 24 hours. This systematic review examines antibiotic regimens and associated infection rates in breast reconstruction.
Evaluating sterile human acellular dermal matrix in immediate expander-based breast reconstruction
Evaluating sterile human acellular dermal matrix in immediate expander-based breast reconstruction: A multicenter, prospective, cohort study. Plastic and reconstructive surgery, Jan. 2013, Vol. 131(1), p.9e-18e.
Venturi, M.L., et al.
http://journals.lww.com/plasreconsurg/Abstract/2013/01000/Evaluating_Sterile_Human_Acellular_Dermal_Matrix.5.aspx
Human acellular dermal matrices have gained increasing use in immediate expander-based breast reconstruction. However, some studies suggest that these grafts may be associated with a higher incidence of infection and seroma. To evaluate complication rates after matrix-based breast reconstruction, the authors conducted a prospective, multicenter, cohort study to evaluate a sterile human acellular dermal matrix in immediate expander-based breast reconstruction, specifically, to determine whether it offered a more favorable risk profile with respect to infection and seroma. A secondary purpose was to determine whether the sterilization process affects graft incorporation.
Venturi, M.L., et al.
http://journals.lww.com/plasreconsurg/Abstract/2013/01000/Evaluating_Sterile_Human_Acellular_Dermal_Matrix.5.aspx
Human acellular dermal matrices have gained increasing use in immediate expander-based breast reconstruction. However, some studies suggest that these grafts may be associated with a higher incidence of infection and seroma. To evaluate complication rates after matrix-based breast reconstruction, the authors conducted a prospective, multicenter, cohort study to evaluate a sterile human acellular dermal matrix in immediate expander-based breast reconstruction, specifically, to determine whether it offered a more favorable risk profile with respect to infection and seroma. A secondary purpose was to determine whether the sterilization process affects graft incorporation.
Comprehensive outcome and cost analysis of free tissue transfer for breast reconstruction
Comprehensive outcome and cost analysis of free tissue transfer for breast reconstruction: An experience with 1303 flaps. Plastic and reconstructive surgery, Feb. 2013, Vol. 131(2), p.195-203.
Fischer, J., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/02000/Comprehensive_Outcome_and_Cost_Analysis_of_Free.4.aspx
Free tissue transfer is standard for postoncologic reconstruction, yet it entails a lengthy operation and significant recovery. The authors present their longitudinal experience of free tissue breast reconstructions with an emphasis on predictors of major surgical and medical complications.
Fischer, J., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/02000/Comprehensive_Outcome_and_Cost_Analysis_of_Free.4.aspx
Free tissue transfer is standard for postoncologic reconstruction, yet it entails a lengthy operation and significant recovery. The authors present their longitudinal experience of free tissue breast reconstructions with an emphasis on predictors of major surgical and medical complications.
Microsurgical breast reconstruction for nipple-sparing mastectomy
Microsurgical breast reconstruction for nipple-sparing mastectomy. Plastic and reconstructive surgery, Feb 2013, Vol. 131(2), p.139(e)-147(e).
Tanna, N., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/02000/Microsurgical_Breast_Reconstruction_for.3.aspx
Nipple-sparing mastectomy warrants thorough preoperative evaluation to effectively achieve risk reduction, high patient satisfaction, and improved aesthetic outcome. To the authors' knowledge, this review represents the largest series of microsurgical breast reconstructions following nipple-sparing mastectomies.
Tanna, N., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2013/02000/Microsurgical_Breast_Reconstruction_for.3.aspx
Nipple-sparing mastectomy warrants thorough preoperative evaluation to effectively achieve risk reduction, high patient satisfaction, and improved aesthetic outcome. To the authors' knowledge, this review represents the largest series of microsurgical breast reconstructions following nipple-sparing mastectomies.
Breast imaging of the pregnant and lactating patient
Breast imaging of the pregnant and lactating patient: Physiologic changes and common benign entities. AJR, Feb. 2013, Vol. 200(2), p.329-336.
Vashi, R., et al.
http://www.ajronline.org/content/200/2/329.abstract
The purpose of this article is to review key clinical, histologic, and imaging features of expected physiologic changes within the breast and common benign breast disease in the pregnant and lactating patient.
Vashi, R., et al.
http://www.ajronline.org/content/200/2/329.abstract
The purpose of this article is to review key clinical, histologic, and imaging features of expected physiologic changes within the breast and common benign breast disease in the pregnant and lactating patient.
Survival is better after lumpectomy than mastectomy in early breast cancer
Survival is better in lumpectomy than mastectomy in early breast cancer. BMJ, 2013, 346:1577.
Mayor, S.
http://www.bmj.com/highwire/filestream/627882/field_highwire_article_pdf/0/bmj.f577
Women with early stage breast cancer who are treated with lumpectomy and radiotherapy have significantly better survival than women who have a mastectomy, a retrospective study of US data has found. Researchers analyzed data in the California cancer registry from all 112 154 women in the state who had been given a diagnosis of early stage, invasive breast cancer between 1990 and 2004 and who were treated with either lumpectomy and radiotherapy or mastectomy and were followed to December 2009.
Mayor, S.
http://www.bmj.com/highwire/filestream/627882/field_highwire_article_pdf/0/bmj.f577
Women with early stage breast cancer who are treated with lumpectomy and radiotherapy have significantly better survival than women who have a mastectomy, a retrospective study of US data has found. Researchers analyzed data in the California cancer registry from all 112 154 women in the state who had been given a diagnosis of early stage, invasive breast cancer between 1990 and 2004 and who were treated with either lumpectomy and radiotherapy or mastectomy and were followed to December 2009.
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