Monday 26 November 2012

Menarche, menopause and breast cancer risk: individual patient meta-analysis

Menarche, menopause and breast cancer risk: individual patient meta-analysis, including 118964 women with breast cancer from 117 epidemiological studies.  The lancet oncology, Nov. 2012, Vol. 13(11), p.1141-1151.

Collaborative group on hormonal factors in breast cancer.

http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(12)70425-4/abstract?rss=yes

Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated with reproduction, and affect breast cancer risk. Our aim was to assess the strengths of their effects and determine whether they depend on characteristics of the tumours or the affected women.