Once is not enough: withholding postoperative prophylactic antibiotics in prosthetic breast reconstruction is associated with an increased risk of infection. Plastic & reconstructive surgery, Sept 2012, Vol. 130(3), p.495-502.
Clayton, J.L., et al.
http://journals.lww.com/plasreconsurg/Abstract/2012/09000/Once_Is_Not_Enough___Withholding_Postoperative.1.aspx
There has been a trend toward limiting perioperative prophylactic antibiotics, based on research not conducted in plastic surgery patients. The authors' university hospital instituted antibiotic prescribing guidelines based on the Surgical Care Improvement Project. An increased rate of surgical-site infections was noted in breast reconstruction patients.
