Tamoixfen increases the risk of microvascular flap complications in patients undergoing microvascular breast reconstruction. Plastic & reconstructive surgery, Feb 2012, Vol. 129(2), p. 305-314.
Kelley, B.P., et al.
http://journals.lww.com/plasreconsurg/Fulltext/2012/02000/Tamoxifen_Increases_the_Risk_of_Microvascular_Flap.3.aspx
Tamoxifen citrate (tamoxifen) has been associated with increased rates of thromboembolic events, prompting concerns that it may increase the risk of complications after microvascular breast reconstruction. Some centers have implemented protocols to temporarily stop tamoxifen before microvascular breast reconstruction. The authors sought to determine whether this practice is warranted.
