Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8.1 years median follow-up. The Lancet Oncology, Vol. 12(12), Nov 2011, p. 1101-1108.
Regan, M.M., et al.
http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(11)70270-4/abstract?rss=yes
Postmenopausal women with hormone receptor-positive early breast cancer have persistent, long-term risk of breast-cancer recurrence and death. Therefore, trials assessing endocrine therapies for this patient population need extended follow-up. We present an update of efficacy outcomes in the Breast International Group (BIG) 1-98 study at 8·1 years median follow-up.
Thursday, 15 December 2011
Influence of histology on the effectiveness of adjuvant chemotherapy
Influence of histology on the effectiveness of adjuvant chemotherapy in patients with hormone receptor positive invasive breast cancer. The Breast, Vol. 20(6), Dec 2011, p. 505-509.
Truin, W., et al.
http://www.thebreastonline.com/article/S0960-9776(11)00121-4/abstract
To investigate the effect of adjuvant chemotherapy on long term survival in addition to hormonal therapy in the systemic treatment of hormonal receptor positive breast cancer patients.
Truin, W., et al.
http://www.thebreastonline.com/article/S0960-9776(11)00121-4/abstract
To investigate the effect of adjuvant chemotherapy on long term survival in addition to hormonal therapy in the systemic treatment of hormonal receptor positive breast cancer patients.
Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer
Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer: A systematic review and meta-analysis. The Breast Vol. 20(6), Dec 2011, p. 485-490.
Valachis, A., et al.
http://www.thebreastonline.com/article/S0960-9776(11)00135-4/abstract
Potentially eligible trials were located through PubMed and Cochrane Library searches and abstracts of major international conferences. The endpoints that we assessed were pathologic complete response (pCR) rate, breast-conserving surgery (BCS) rate and toxicity.
Valachis, A., et al.
http://www.thebreastonline.com/article/S0960-9776(11)00135-4/abstract
Potentially eligible trials were located through PubMed and Cochrane Library searches and abstracts of major international conferences. The endpoints that we assessed were pathologic complete response (pCR) rate, breast-conserving surgery (BCS) rate and toxicity.
Intraveneous fluid infusion rate in microsurgical breast reconstruction
Intraveneous fluid infusion rate in microsurgical breast reconstruction: Important lessons learned from 354 free flaps. Plastic & reconstructive surgery, Dec 2011, Vol. 128(6), p. 1153-1160.
Zhong, T., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/Intravenous_Fluid_Infusion_Rate_in_Microsurgical.1.aspx
The purpose of this study was to determine the role of intravenous fluid infusion rate in the development of in-hospital complications in patients undergoing microsurgical breast reconstruction for breast cancer.
Zhong, T., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/Intravenous_Fluid_Infusion_Rate_in_Microsurgical.1.aspx
The purpose of this study was to determine the role of intravenous fluid infusion rate in the development of in-hospital complications in patients undergoing microsurgical breast reconstruction for breast cancer.
Simultaneous scarless contralateral breast augmentation
Simultaneous scarless contralateral breast augmentation during unilateral breast reconstruction using bilateral differentially split DIEP flaps. Plastic & reconstructive surgery, Dec 2011, Vol 128(6), p. 593e-604e.
Huang, J-J., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/Simultaneous_Scarless_Contralateral_Breast.6.aspx
Simultaneous contralateral augmentation is performed with unilateral breast reconstruction to achieve pleasing and symmetric breast mounds. This prospective study investigated the outcome of simultaneous scarless contralateral augmentation with unilateral breast reconstruction using bilateral differentially split deep inferior epigastric perforator (DIEP) flaps.
Huang, J-J., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/Simultaneous_Scarless_Contralateral_Breast.6.aspx
Simultaneous contralateral augmentation is performed with unilateral breast reconstruction to achieve pleasing and symmetric breast mounds. This prospective study investigated the outcome of simultaneous scarless contralateral augmentation with unilateral breast reconstruction using bilateral differentially split deep inferior epigastric perforator (DIEP) flaps.
The lateral chest wall: A separate aesthetic unit in breast surgery
The lateral chest wall: A separate aesthetic unit in breast surgery. Plastic and reconstructive surgery; Dec 2011, Vol. 128(6), p. 626e - 643e.
Bar-Meir, E.D., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/The_Lateral_Chest_Wall___A_Separate_Aesthetic_Unit.13.aspx
The lateral chest wall is an aesthetic unit often overlooked in breast surgery. Abnormalities are often seen in candidates for aesthetic and reconstructive breast surgery and in the massive weight loss population. Preoperative evaluation of the lateral chest wall is necessary to address this area properly.
Bar-Meir, E.D., et al.
http://journals.lww.com/plasreconsurg/Abstract/2011/12000/The_Lateral_Chest_Wall___A_Separate_Aesthetic_Unit.13.aspx
The lateral chest wall is an aesthetic unit often overlooked in breast surgery. Abnormalities are often seen in candidates for aesthetic and reconstructive breast surgery and in the massive weight loss population. Preoperative evaluation of the lateral chest wall is necessary to address this area properly.
Pertuzumab plus Trastuzumab plus Docetaxel for metastatic breast cancer
Pertuzumab plus Trastuzumab plus Docetaxel for metastatic breast cancer. N Eng J Med, Dec 2011.
Baselga, J., et al.
http://www.nejm.org/doi/full/10.1056/NEJMoa1113216#t=article
The anti–human epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody trastuzumab improves the outcome in patients with HER2-positive metastatic breast cancer. However, most cases of advanced disease eventually progress.
Baselga, J., et al.
http://www.nejm.org/doi/full/10.1056/NEJMoa1113216#t=article
The anti–human epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody trastuzumab improves the outcome in patients with HER2-positive metastatic breast cancer. However, most cases of advanced disease eventually progress.
Evedrolimus in postmenopausal hormone-receptor-positive advanced breast cancer
Evedrolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Eng J. Med, Dec 2011
Baselga, J., et al.
http://www.nejm.org/doi/full/10.1056/NEJMoa1109653#t=article
Endocrine therapy is the cornerstone of treatment for patients with hormone-receptor (HR)–positive advanced breast cancer. In postmenopausal patients, aromatase inhibitors (e.g., letrozole and anastrozole) have become the treatment of choice in first-line therapy. Unfortunately, not all patients have a response to first-line endocrine therapy (primary or de novo resistance), and even patients who have a response will eventually relapse (acquired resistance).
Baselga, J., et al.
http://www.nejm.org/doi/full/10.1056/NEJMoa1109653#t=article
Endocrine therapy is the cornerstone of treatment for patients with hormone-receptor (HR)–positive advanced breast cancer. In postmenopausal patients, aromatase inhibitors (e.g., letrozole and anastrozole) have become the treatment of choice in first-line therapy. Unfortunately, not all patients have a response to first-line endocrine therapy (primary or de novo resistance), and even patients who have a response will eventually relapse (acquired resistance).
Disappearance of a breast prosthesis during Pilates
Disappearance of a breast prosthesis during Pilates. N Eng J Med., 2011, 365:2305
Fong, T.C., and Hoffmann, B.
http://www.nejm.org/doi/full/10.1056/NEJMicm1102594
A 59-year-old woman with a history of breast cancer who underwent bilateral mastectomy and placement of breast prostheses presented for evaluation, reporting that her “body swallowed one of the implants” during a Pilates stretching exercise.
Fong, T.C., and Hoffmann, B.
http://www.nejm.org/doi/full/10.1056/NEJMicm1102594
A 59-year-old woman with a history of breast cancer who underwent bilateral mastectomy and placement of breast prostheses presented for evaluation, reporting that her “body swallowed one of the implants” during a Pilates stretching exercise.
Minor influence of self-selection bias on the effectiveness of breast cancer screening in case-control studies in the Netherlands
Minor influence of self-selection bias on the effectiveness of breast cancer screening in case-control studies in the Netherlands. Journal of medical screening, Sept 2011, Vol. 18(3), p. 142-146
Paap, E., et al.
http://jms.rsmjournals.com/content/18/3/142.short?rss=1
Self-selection bias is considered to be a problem when evaluating the effectiveness of breast cancer service screening in case-control studies. Using the incidence-based mortality method (IBM), a correction factor for the potential influence of self-selection can be derived from a group of non-screened women and a group of not-invited women.
Paap, E., et al.
http://jms.rsmjournals.com/content/18/3/142.short?rss=1
Self-selection bias is considered to be a problem when evaluating the effectiveness of breast cancer service screening in case-control studies. Using the incidence-based mortality method (IBM), a correction factor for the potential influence of self-selection can be derived from a group of non-screened women and a group of not-invited women.
Challenges in mammography Part II: Multimodality of breast augmentation
Challenges in mammography Part II: Multimodality of breast augmention - imaging findings and complications. AJR, Dec 2011, Vol 197(6), p. W1031-W1045
Venkataraman, S. et al.
http://www.ajronline.org/content/197/6/W1031.abstract
Breast augmentation is common throughout the world; however, there is variation in materials and surgical techniques. This review illustrates the mammographic, sonographic, and MRI characteristics of the different types of breast augmentation, including silicone, saline, polyacrylamide gel, and autologous fat augmentation.
Venkataraman, S. et al.
http://www.ajronline.org/content/197/6/W1031.abstract
Breast augmentation is common throughout the world; however, there is variation in materials and surgical techniques. This review illustrates the mammographic, sonographic, and MRI characteristics of the different types of breast augmentation, including silicone, saline, polyacrylamide gel, and autologous fat augmentation.
Challenges in mammography Part I: Artifacts in digital mammography
Challenges in mammography Part I: Artifacts in digital mammography. AJR, Dec 2011, Vol 197(6), p. W1023-W1030
Geiser, W.R., et al.
http://www.ajronline.org/content/197/6/W1023.abstract?rss=1
Early detection of breast cancer is directly related to the radiologist’s ability to detect abnormalities visible only on mammograms. Artifacts on mammograms reduce image quality and may present clinical and technical difficulties for the radiologist, mammography technologist, medical physicist, and equipment service personnel.
Geiser, W.R., et al.
http://www.ajronline.org/content/197/6/W1023.abstract?rss=1
Early detection of breast cancer is directly related to the radiologist’s ability to detect abnormalities visible only on mammograms. Artifacts on mammograms reduce image quality and may present clinical and technical difficulties for the radiologist, mammography technologist, medical physicist, and equipment service personnel.
Impact on breast cancer diagnosis in a multidisciplinary unit after the incorporation of mammography digitalization
Impact on breast cancer diagnosis in a multidisciplinary unit after the incorporation of mammography digitalization and computer-aided detection systems. AJR, Dec 2011, Vol 197(6), p. 1492-97.
Romero, C., et al.
http://www.ajronline.org/content/197/6/1492.abstract?rss=1
The purpose of this article is to evaluate the impact on the diagnosis of breast cancer of implementing full-field digital mammography (FFDM) in a multidisciplinary breast pathology unit and, 1 year later, the addition of a computer-aided detection (CAD) system.
Romero, C., et al.
http://www.ajronline.org/content/197/6/1492.abstract?rss=1
The purpose of this article is to evaluate the impact on the diagnosis of breast cancer of implementing full-field digital mammography (FFDM) in a multidisciplinary breast pathology unit and, 1 year later, the addition of a computer-aided detection (CAD) system.
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